This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Hypothyroidism and >3 levothyroxin purchases
HYPOTHY_PURCHASE
hypothyroidism: Abnormally low levels of thyroid hormone.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditions
|
54806 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
54077 |
6. Filter based on genotype QC (FinnGen only) |
52222 |
Control definitions (FinnGen only)
Control exclude
E4_MALNUTRITION, E4_DIABETES, I9_CVD, C3_CANCER, MENINGITIS, ENCEPHALITIS, HYPOTHYROIDISM, D3_ANAEMIA, F5_ALLANXIOUS, F5_MOOD, F5_SCHIZO, F5_BEHEMOCHILD, F5_UNSMENDIS, ANOSMIA, ANTIDEPRESSANTS
Control conditions
not HYPOTHYROIDISM
Extra metadata
First used in FinnGen datafreeze
DF3
Similar endpoints
↥List of similar endpoints to
Hypothyroidism and >3 levothyroxin purchases
based on the number of shared cases.
Broader endpoints:
- Hypothyroidism, levothyroxine purchases
- Hypothyroidism, other/unspecified
- Hypothyroidism (congenital or acquired)
- Disorders of the thyroid gland
- Used for control exclusion in common control thyroid runs
Narrower endpoints:
Case counts by codes
↥FinnGen case counts by registry codes:
No data for upset plot.
No data for upset table.
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 52222 | 41726 | 10496 |
| Unadjusted period prevalence (%) | 15.64 | 18.12 | 5.77 |
| Median age at first event (years) | 52.93 | 51.11 | 60.17 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: HYPOTHY_PURCHASE – Hypothyroidism and >3 levothyroxin purchases
GWS hits: -
Loading Relationships table