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Schizophrenia, schizotypal and delusional disorders


schizophrenia: A major psychotic disorder characterized by abnormalities in the perception or expression of reality. It affects the cognitive and psychomotor functions. Common clinical signs and symptoms include delusions, hallucinations, disorganized thinking, and retreat from reality.

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Endpoint definition

Endpoint definition steps


Phenotype data


1. Apply sex-specific rule



2. Check conditions



3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F20
  • Cause of death: ICD-10 F20

2 out of 7 registries used, show all original rules.


4. Check minimum number of events



5. Include endpoints


6. Filter based on genotype QC (FinnGen only)


Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F20-F29
Name in latin Schizophrenia

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics


This endpoint is excluded from FinRegistry analyses (omitted endpoint).


Key figures

All Female Male
Number of individuals 13794 7179 6615
Unadjusted period prevalence (%) 3.37 3.12 3.64
Median age at first event (years) 30.81 31.80 29.73


Age distribution of first events


Year distribution of first events


Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: F5_SCHIZO – Schizophrenia, schizotypal and delusional disorders

GWS hits: -

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