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Acute and transient psychotic disorders

DOID EFO Endpoint Browser PheWeb

F5_PSYTRANS

psychosis: An abnormal condition of the mind that involves a loss of contact with reality. People experiencing psychosis may exhibit personality changes and thought disorder. Depending on its severity, this may be accompanied by unusual or bizarre behavior, as well as difficulty with social interaction and impairment in carrying out daily life activities.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — F23
  • Hospital discharge: ICD-9 — 298
  • Hospital discharge: ICD-8 — 298
  • Hospital discharge: excluded ICD-8 — 2989
  • Cause of death: ICD-10 — F23
  • Cause of death: ICD-9 — 298
  • Cause of death: ICD-8 — 298
  • Cause of death: excluded ICD-8 — 2989

2 out of 7 registries used, show all original rules.

4672

4. Check minimum number of events

None

4672

5. Include endpoints

None

4672

6. Filter based on genotype QC (FinnGen only)

4463

Control definitions (FinnGen only)

Control exclude F5_SCHIZO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F20-F29
Name in latin Perturbationes psychoticae acutae et temporariae

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 53547 27877 25065
Only index persons 42141 22526 19615
Unadjusted period prevalence (%)
Whole population 0.75 0.80 0.70
Only index persons 0.79 0.83 0.75
Median age at first event (years)
Whole population 36.49 38.96 33.50
Only index persons 34.11 36.47 31.40

-FinnGen-

Key figures

All Female Male
Number of individuals 4463 2464 1999
Unadjusted period prevalence (%) 1.08 1.07 1.10
Median age at first event (years) 31.04 31.94 29.92

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: F5_PSYTRANS – Acute and transient psychotic disorders

GWS hits: 2

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