Schizoaffective disorder

F5_SCHIZOAFF

schizoaffective disorder: A disorder in which the individual suffers from both symptoms that qualify as schizophrenia and symptoms that qualify as a mood disorder (e.g., depression or bipolar disorder) for a substantial portion (but not all) of the active period of the illness; for the remainder of the active period of the illness, the individual suffers from delusions or hallucinations in the absence of prominent mood symptoms.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F25
  • Hospital discharge: ICD-9 2957
  • Hospital discharge: ICD-8 2957
  • Cause of death: ICD-10 F25
  • Cause of death: ICD-9 2957
  • Cause of death: ICD-8 2957

2 out of 7 registries used, show all original rules.

2963

4. Check minimum number of events

None

2963

5. Include endpoints

None

2963

6. Filter based on genotype QC (FinnGen only)

2837

Control definitions (FinnGen only)

Control exclude F5_SCHIZO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F20-F29
Name in latin Perturbationes schizoaffectivae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 19879 11140 8568
Only index persons 17035 9776 7259
Unadjusted period prevalence (%)
Whole population 0.28 0.32 0.24
Only index persons 0.32 0.36 0.28
Median age at first event (years)
Whole population 37.27 38.72 35.28
Only index persons 36.54 37.90 34.70

-FinnGen-

Key figures

All Female Male
Number of individuals 2837 1672 1165
Unadjusted period prevalence (%) 0.69 0.73 0.64
Median age at first event (years) 35.18 35.61 34.56

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: F5_SCHIZOAFF – Schizoaffective disorder

GWS hits: 1

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