Depression medications

ANTIDEPRESSANTS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

124934

6. Filter based on genotype QC (FinnGen only)

120443

Control definitions (FinnGen only)

Control exclude NEURO_COMORBIDITIES

Extra metadata

First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1301037 797631 495459
Only index persons 1186033 738521 447512
Unadjusted period prevalence (%)
Whole population 19.33 22.85 13.84
Only index persons 23.35 27.15 17.08
Median age at first event (years)
Whole population 45.17 45.51 44.51
Only index persons 43.34 43.69 42.76

-FinnGen-

Key figures

All Female Male
Number of individuals 120443 78493 41950
Unadjusted period prevalence (%) 30.25 34.09 23.07
Median age at first event (years) 44.85 42.54 49.18

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: ANTIDEPRESSANTS – Depression medications

GWS hits: 35

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