anxiety disorder: A category of psychiatric disorders which are characterized by anxious feelings or fear often accompanied by physical symptoms associated with anxiety.
Endpoint definition
↥
						Endpoint definition steps | 
					
						FinnGen | 
				
|---|---|
						Phenotype data | 
					429209 | 
								1. Apply sex-specific ruleNone  | 
							429209 | 
								2. Check conditionsNone  | 
							429209 | 
								3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules.  | 
							
								 0  | 
						
								4. Check minimum number of eventsNone  | 
							0 | 
								5. Include endpoints | 
							28942 | 
										6. Filter based on genotype QC (FinnGen only) | 
									27663 | 
Control definitions (FinnGen only)
					Control exclude
					F5_NEUROTIC
				
			Extra metadata
					Level in the ICD hierarchy
					3
				
				
					First used in FinnGen datafreeze
					DF2
				
			Similar endpoints
↥List of similar endpoints to
		
All anxiety disorders
	based on the number of shared cases.
		
		Broader endpoints:
	
- Anxiety (asthma-related co-morbidities)
 - Neurotic, stress-related and somatoform disorders
 - Anxiety disorders (more control exclusions)
 - Anxiety disorders
 - Any mental disorder
 
		
		Narrower endpoints:
	
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 347111 | 210940 | 134201 | 
| Only index persons | 328303 | 202993 | 125310 | 
| Unadjusted period prevalence (%) | |||
| Whole population | 5.13 | 6.04 | 3.75 | 
| Only index persons | 6.44 | 7.46 | 4.78 | 
| Median age at first event (years) | |||
| Whole population | 29.17 | 29.49 | 28.58 | 
| Only index persons | 28.72 | 29.04 | 28.21 | 
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 27663 | 19237 | 8426 | 
| Unadjusted period prevalence (%) | 7.22 | 8.35 | 4.63 | 
| Median age at first event (years) | 34.99 | 34.18 | 36.84 | 
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: F5_ALLANXIOUS – All anxiety disorders
GWS hits: 6
                
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