Anxiety disorders (more control exclusions)

KRA_PSY_ANXIETY_EXMORE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F40-F48
  • Hospital discharge: ICD-9 300[0-3|6-9]|3078A|309
  • Hospital discharge: ICD-8 300[0-2]|30030|300[5-9]|305|30680|30799
  • Cause of death: ICD-10 F40-F48
  • Cause of death: ICD-9 300[0-3|6-9]|3078A|309
  • Cause of death: ICD-8 300[0-2]|30030|300[5-9]|305|30680|30799

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude KRA_PSY_ANYMENTAL

Extra metadata

First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

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Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 534702 319646 211486
Only index persons 494695 301970 192725
Unadjusted period prevalence (%)
Whole population 7.84 9.16 5.91
Only index persons 9.64 11.10 7.36
Median age at first event (years)
Whole population 31.24 32.68 28.98
Only index persons 30.42 31.83 28.21

-FinnGen-

Key figures

All Female Male
Number of individuals 44662 30694 13968
Unadjusted period prevalence (%) 11.56 13.33 7.68
Median age at first event (years) 36.84 36.39 37.82

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: KRA_PSY_ANXIETY_EXMORE – Anxiety disorders (more control exclusions)

GWS hits: 17

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