Obsessive-compulsive disorder

F5_OCD

obsessive-compulsive disorder: A disorder characterized by the presence of persistent and recurrent irrational thoughts (obsessions), resulting in marked anxiety and repetitive excessive behaviors (compulsions) as a way to try to decrease that anxiety.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F42
  • Hospital discharge: ICD-9 3003
  • Hospital discharge: ICD-8 3003
  • Cause of death: ICD-10 F42
  • Cause of death: ICD-9 3003
  • Cause of death: ICD-8 3003

2 out of 7 registries used, show all original rules.

2275

4. Check minimum number of events

None

2275

5. Include endpoints

None

2275

6. Filter based on genotype QC (FinnGen only)

2175

Control definitions (FinnGen only)

Control exclude F5_NEUROTIC

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F40-F48
Name in latin Perturbatio obsessivo-compulsiva

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 29148 16764 12270
Only index persons 27884 16218 11666
Unadjusted period prevalence (%)
Whole population 0.42 0.48 0.34
Only index persons 0.53 0.60 0.45
Median age at first event (years)
Whole population 24.97 25.04 24.81
Only index persons 24.80 24.90 24.66

-FinnGen-

Key figures

All Female Male
Number of individuals 2175 1418 757
Unadjusted period prevalence (%) 0.55 0.62 0.42
Median age at first event (years) 29.91 28.94 31.74

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: F5_OCD – Obsessive-compulsive disorder

GWS hits: -

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