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Generalized anxiety disorder

DOID EFO Endpoint Browser PheWeb

F5_GAD

generalized anxiety disorder: An anxiety disorder that is characterized by long-lasting anxiety that is not focused on any one object or situation.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — F41.1
  • Hospital discharge: ICD-9 — 3000C
  • Cause of death: ICD-10 — F41.1
  • Cause of death: ICD-9 — 3000C

2 out of 7 registries used, show all original rules.

5478

4. Check minimum number of events

None

5478

5. Include endpoints

None

5478

6. Filter based on genotype QC (FinnGen only)

5279

Control definitions (FinnGen only)

Control exclude F5_NEUROTIC

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F41
Name in latin Perturbatio anxifera generalisata

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 55293 36531 18494
Only index persons 53023 35440 17583
Unadjusted period prevalence (%)
Whole population 0.87 1.05 0.52
Only index persons 1.09 1.30 0.67
Median age at first event (years)
Whole population 34.12 33.83 34.65
Only index persons 33.53 33.25 34.10

-FinnGen-

Key figures

All Female Male
Number of individuals 5279 3845 1434
Unadjusted period prevalence (%) 1.43 1.67 0.79
Median age at first event (years) 38.23 37.51 40.17

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: F5_GAD – Generalized anxiety disorder

GWS hits: 1

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