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Hypothyroidism (congenital or acquired)

HYPOTHYROIDISM

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

54806

6. Filter based on genotype QC (FinnGen only)

52929

Control definitions (FinnGen only)

Control exclude NEURO_COMORBIDITIES

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Hypothyroidism (congenital or acquired) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 52929 42189 10740
Unadjusted period prevalence (%) 15.80 18.32 5.91
Median age at first event (years) 52.83 50.97 60.16

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: HYPOTHYROIDISM – Hypothyroidism (congenital or acquired)

GWS hits: -

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