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Hypothyroidism (congenital or acquired)

HYPOTHYROIDISM

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

54806

6. Filter based on genotype QC (FinnGen only)

52929

Control definitions (FinnGen only)

Control exclude NEURO_COMORBIDITIES

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Hypothyroidism (congenital or acquired) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Case counts by codes

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FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

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-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 52929 42189 10740
Unadjusted period prevalence (%) 15.80 18.32 5.91
Median age at first event (years) 52.83 50.97 60.16

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

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This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

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Index endpoint: HYPOTHYROIDISM – Hypothyroidism (congenital or acquired)

GWS hits: -

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