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This is a non-core endpoint: only basic statistics are computed.

Iodine-deficiency-related goitre

E4_IODGOITRE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E01
  • Hospital discharge: excluded ICD-10 E01.8
  • Cause of death: ICD-10 E01
  • Cause of death: excluded ICD-10 E01.8

2 out of 7 registries used, show all original rules.

35

4. Check minimum number of events

None

35

5. Include endpoints

None

35

6. Filter based on genotype QC (FinnGen only)

34

Control definitions (FinnGen only)

Control exclude E4_THYROID

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E00-E07
Name in latin Morbositates glandulae thyreoideae ex deficientia iodi et status cognati

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 352 252 94
Only index persons 293 222 71
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.00
Only index persons 0.01 0.01 0.00
Median age at first event (years)
Whole population 57.83 57.85 56.58
Only index persons 53.36 55.22 47.56

-FinnGen-

Key figures

All Female Male
Number of individuals 34 24 10
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 56.63 58.17 52.95

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: E4_IODGOITRE – Iodine-deficiency-related goitre

GWS hits: -

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