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Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT

E4_HYTHY_AI_EXCL

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E8901|E8909|E23|D352|E0382|E05[1-9]|E0[0-2]
  • Hospital discharge: ICD-9 253
  • Hospital discharge: ICD-8 253
  • Cause of death: ICD-10 E8901|E8909|E23|D352|E0382|E05[1-9]|E0[0-2]
  • Cause of death: ICD-9 253
  • Cause of death: ICD-8 253
  • Operations: NOMESCO codes ^BAA60

3 out of 7 registries used, show all original rules.

12423

4. Check minimum number of events

None

12423

5. Include endpoints

None

12423

6. Filter based on genotype QC (FinnGen only)

11984

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 11984 8461 3523
Unadjusted period prevalence (%) 3.16 3.67 1.94
Median age at first event (years) 54.10 52.97 56.81

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: E4_HYTHY_AI_EXCL – Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT

GWS hits: -

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