Thyrotoxicosis

THYROTOXICOSIS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

9174

6. Filter based on genotype QC (FinnGen only)

8872

Control definitions (FinnGen only)

Control exclude THYROID_DISORDER_IBD

Extra metadata

First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 77269 61676 14979
Only index persons 67659 54737 12922
Unadjusted period prevalence (%)
Whole population 1.50 1.77 0.42
Only index persons 1.72 2.01 0.49
Median age at first event (years)
Whole population 54.48 53.92 57.07
Only index persons 52.97 52.26 55.95

-FinnGen-

Key figures

All Female Male
Number of individuals 8872 7019 1853
Unadjusted period prevalence (%) 2.62 3.05 1.02
Median age at first event (years) 52.39 50.54 59.40

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: THYROTOXICOSIS – Thyrotoxicosis

GWS hits: 30

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