No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditions
|
5017 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
2061 |
4. Check minimum number of eventsNone |
2061 |
5. Include endpointsNone |
2061 |
6. Filter based on genotype QC (FinnGen only) |
1991 |
Control definitions (FinnGen only)
Control exclude
AUTOIMMUNE
Control conditions
not E4_THYTOXGOITDIF
Extra metadata
First used in FinnGen datafreeze
DF5
Similar endpoints
↥List of similar endpoints to
Autoimmune hyperthyroidism
based on the number of shared cases.
Broader endpoints:
- Thyrotoxicosis with diffuse goitre
- Thyrotoxicosis, other and/or unspecified
- Thyrotoxicosis
- Disorders of thyroid, IBD co-morbidities
- Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT
Narrower endpoints:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 14824 | 11965 | 2766 |
| Only index persons | 14358 | 11690 | 2668 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.29 | 0.34 | 0.08 |
| Only index persons | 0.37 | 0.43 | 0.10 |
| Median age at first event (years) | |||
| Whole population | 50.67 | 50.39 | 52.43 |
| Only index persons | 50.46 | 50.13 | 51.92 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1991 | 1647 | 344 |
| Unadjusted period prevalence (%) | 0.62 | 0.72 | 0.19 |
| Median age at first event (years) | 50.54 | 49.44 | 55.83 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: AUTOIMMUNE_HYPERTHYROIDISM – Autoimmune hyperthyroidism
GWS hits: 9
Loading Relationships table