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This is a non-core endpoint: only basic statistics are computed.

Thyrotoxicosis from ectopic thyroid tissue

E4_THYTOXECT

Hyperthyroidism: Overactivity of the thyroid gland resulting in overproduction of thyroid hormone and increased metabolic rate. Causes include diffuse hyperplasia of the thyroid gland (Graves' disease), single nodule in the thyroid gland, and thyroiditis. The symptoms are related to the increased metabolic rate and include weight loss, fatigue, heat intolerance, excessive sweating, diarrhea, tachycardia, insomnia, muscle weakness, and tremor.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E05.3
  • Hospital discharge: ICD-9 2424
  • Cause of death: ICD-10 E05.3
  • Cause of death: ICD-9 2424

2 out of 7 registries used, show all original rules.

26

4. Check minimum number of events

None

26

5. Include endpoints

None

26

6. Filter based on genotype QC (FinnGen only)

24

Control definitions (FinnGen only)

Control exclude E4_THYROID

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E05
Name in latin Thyreotoxicosis ex textu thyreoideo ectopico

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 264 203 60
Only index persons 240 191 49
Unadjusted period prevalence (%)
Whole population 0.00 0.01 0.00
Only index persons 0.01 0.01 0.00
Median age at first event (years)
Whole population 50.00 48.78 54.61
Only index persons 48.42 47.52 51.91

-FinnGen-

Key figures

All Female Male
Number of individuals 24 23 -
Unadjusted period prevalence (%) 0.01 0.01 -
Median age at first event (years) 43.46 42.79 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: E4_THYTOXECT – Thyrotoxicosis from ectopic thyroid tissue

GWS hits: -

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