This is a non-core endpoint: only basic statistics are computed.
Thyrotoxicosis from ectopic thyroid tissue
E4_THYTOXECT
Hyperthyroidism: Overactivity of the thyroid gland resulting in overproduction of thyroid hormone and increased metabolic rate. Causes include diffuse hyperplasia of the thyroid gland (Graves' disease), single nodule in the thyroid gland, and thyroiditis. The symptoms are related to the increased metabolic rate and include weight loss, fatigue, heat intolerance, excessive sweating, diarrhea, tachycardia, insomnia, muscle weakness, and tremor.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditionsNone |
429209 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
26 |
4. Check minimum number of eventsNone |
26 |
5. Include endpointsNone |
26 |
6. Filter based on genotype QC (FinnGen only) |
24 |
Control definitions (FinnGen only)
Control exclude
E4_THYROID
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
E05
Name in latin
Thyreotoxicosis ex textu thyreoideo ectopico
Similar endpoints
↥List of similar endpoints to
Thyrotoxicosis from ectopic thyroid tissue
based on the number of shared cases.
Broader endpoints:
- Thyrotoxicosis
- Disorders of thyroid, IBD co-morbidities
- Disorders of the thyroid gland
- Used for control exclusion in common control thyroid runs
- Endocrine, nutritional and metabolic diseases
Narrower endpoints:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 264 | 203 | 60 |
| Only index persons | 240 | 191 | 49 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.00 | 0.01 | 0.00 |
| Only index persons | 0.01 | 0.01 | 0.00 |
| Median age at first event (years) | |||
| Whole population | 50.00 | 48.78 | 54.61 |
| Only index persons | 48.42 | 47.52 | 51.91 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 24 | 23 | - |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | - |
| Median age at first event (years) | 43.46 | 42.79 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: E4_THYTOXECT – Thyrotoxicosis from ectopic thyroid tissue
GWS hits: -
Loading Relationships table