No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditions
|
7068 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
3293 |
6. Filter based on genotype QC (FinnGen only) |
3176 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
First used in FinnGen datafreeze
DF7
Similar endpoints
↥List of similar endpoints to
Graves disease, strict definition
based on the number of shared cases.
Broader endpoints:
- Carbimazole or st.post thyroidectomy, condition for graves disease
- Thyrotoxicosis
- Disorders of thyroid, IBD co-morbidities
- Disorders of the thyroid gland
- Used for control exclusion in common control thyroid runs
Narrower endpoints:
None
Case counts by codes
↥FinnGen case counts by registry codes:
No data for upset plot.
No data for upset table.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 23064 | 18836 | 4057 |
| Only index persons | 22484 | 18513 | 3971 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.46 | 0.54 | 0.11 |
| Only index persons | 0.59 | 0.68 | 0.15 |
| Median age at first event (years) | |||
| Whole population | 49.31 | 49.21 | 50.36 |
| Only index persons | 49.26 | 49.12 | 49.95 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3176 | 2689 | 487 |
| Unadjusted period prevalence (%) | 1.03 | 1.17 | 0.27 |
| Median age at first event (years) | 49.81 | 49.12 | 53.61 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: E4_GRAVES_STRICT – Graves disease, strict definition
GWS hits: 14
Loading Relationships table