Graves ophthalmopathy, strict

E4_GRAVES_OPHT_STRICT

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

622

4. Check minimum number of events

None

622

5. Include endpoints

None

622

6. Filter based on genotype QC (FinnGen only)

598

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF7

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3679 2975 690
Only index persons 3569 2906 663
Unadjusted period prevalence (%)
Whole population 0.07 0.09 0.02
Only index persons 0.09 0.11 0.03
Median age at first event (years)
Whole population 51.38 51.28 51.88
Only index persons 51.22 51.20 51.31

-FinnGen-

Key figures

All Female Male
Number of individuals 598 484 114
Unadjusted period prevalence (%) 0.18 0.21 0.06
Median age at first event (years) 52.70 52.37 54.13

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: E4_GRAVES_OPHT_STRICT – Graves ophthalmopathy, strict

GWS hits: -

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