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Hypothyroidism, other/unspecified

E4_HYTHYNAS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E03.80, E03.82, E03.89, E03.9, E03.9+F02.89, E03.9+G13.2, E03.9+M14.5
  • Hospital discharge: ICD-9 244[8-9]
  • Hospital discharge: ICD-8 244
  • Hospital discharge: excluded ICD-9 2448A|2448B
  • Hospital discharge: excluded ICD-8 24409
  • Cause of death: ICD-10 E03.80, E03.82, E03.89, E03.9, E03.9+F02.89, E03.9+G13.2, E03.9+M14.5
  • Cause of death: ICD-9 244[8-9]
  • Cause of death: ICD-8 244
  • Cause of death: excluded ICD-9 2448A|2448B
  • KELA reimbursements: KELA codes 104
  • KELA reimbursements: ICD-10 E03
  • Medicine purchases: ATC H03A

4 out of 7 registries used, show all original rules.

54702

4. Check minimum number of events

Min. number of events 3
54702

5. Include endpoints

None

54702

6. Filter based on genotype QC (FinnGen only)

52828

Control definitions (FinnGen only)

Control exclude E4_THYROID

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF9
Name in latin Alia hepatitis viralis acuta

Similar endpoints

List of similar endpoints to Hypothyroidism, other/unspecified based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 52828 42133 10695
Unadjusted period prevalence (%) 15.78 18.30 5.88
Median age at first event (years) 52.83 50.97 60.17

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: E4_HYTHYNAS – Hypothyroidism, other/unspecified

GWS hits: -

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