No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditions
|
416786 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
46925 |
6. Filter based on genotype QC (FinnGen only) |
45320 |
Control definitions (FinnGen only)
Control exclude
AUTOIMMUNE
Control conditions
not E4_HYTHY_AI_EXCL
Extra metadata
First used in FinnGen datafreeze
DF7
Similar endpoints
↥List of similar endpoints to
Hypothyroidism, strict autoimmune
based on the number of shared cases.
Broader endpoints:
- Hypothyroidism, other/unspecified
- Hypothyroidism (congenital or acquired)
- Hypothyreosis and Thyroxine purchase for inclusion criteria
- Disorders of the thyroid gland
- Autoimmune diseases
Narrower endpoints:
Case counts by codes
↥FinnGen case counts by registry codes:
No data for upset plot.
No data for upset table.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 419373 | 331912 | 84867 |
| Only index persons | 387019 | 309390 | 77629 |
| Unadjusted period prevalence (%) | |||
| Whole population | 8.02 | 9.51 | 2.37 |
| Only index persons | 9.69 | 11.37 | 2.96 |
| Median age at first event (years) | |||
| Whole population | 56.15 | 55.15 | 60.28 |
| Only index persons | 55.15 | 54.09 | 59.38 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 45320 | 36229 | 9091 |
| Unadjusted period prevalence (%) | 13.58 | 15.73 | 5.00 |
| Median age at first event (years) | 52.90 | 50.93 | 60.77 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: E4_HYTHY_AI_STRICT – Hypothyroidism, strict autoimmune
GWS hits: 199
Loading Relationships table