endocrine system disease: A disease involving the endocrine system.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditionsNone |
429209 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
13327 |
4. Check minimum number of eventsNone |
13327 |
5. Include endpoints |
17600 |
6. Filter based on genotype QC (FinnGen only) |
16892 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Disorders of other endocrine glands
based on the number of shared cases.
Broader endpoints:
Narrower endpoints:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 187093 | 127000 | 58603 |
| Only index persons | 151332 | 103223 | 48109 |
| Unadjusted period prevalence (%) | |||
| Whole population | 2.99 | 3.64 | 1.64 |
| Only index persons | 3.17 | 3.79 | 1.84 |
| Median age at first event (years) | |||
| Whole population | 51.72 | 55.98 | 42.27 |
| Only index persons | 48.90 | 52.09 | 42.05 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 16892 | 11340 | 5552 |
| Unadjusted period prevalence (%) | 4.31 | 4.92 | 3.05 |
| Median age at first event (years) | 51.03 | 48.55 | 56.09 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: E4_ENDOGLAND – Disorders of other endocrine glands
GWS hits: 4
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