No definition available.
Endpoint definition
↥| Endpoint definition steps | FinnGen | 
|---|---|
| Phenotype data | 429209 | 
| 1. Apply sex-specific ruleNone | 429209 | 
| 2. Check conditionsNone | 429209 | 
| 3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. | 63 | 
| 4. Check minimum number of eventsNone | 63 | 
| 5. Include endpoints | 71 | 
| 6. Filter based on genotype QC (FinnGen only) | 71 | 
Control definitions (FinnGen only)
					Control exclude
					E4_ENDOGLAND
				
			Extra metadata
					Level in the ICD hierarchy
					3
				
				
					First used in FinnGen datafreeze
					DF2
				
				
					Parent code in ICD-10
					E20-E35
				
				
					Name in latin
					Dysfunctio polyglandularis (endocrina)
				
			Similar endpoints
↥List of similar endpoints to
		
Polyglandular dysfunction
	based on the number of shared cases.
		
		Broader endpoints:
	
- Disorders of other endocrine glands
- Endocrine, nutritional and metabolic diseases
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
		
		Narrower endpoints:
	
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 523 | 320 | 196 | 
| Only index persons | 419 | 270 | 149 | 
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 | 
| Only index persons | 0.01 | 0.01 | 0.01 | 
| Median age at first event (years) | |||
| Whole population | 38.73 | 38.37 | 38.89 | 
| Only index persons | 35.72 | 35.52 | 36.08 | 
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 71 | 46 | 25 | 
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.01 | 
| Median age at first event (years) | 33.02 | 36.10 | 27.34 | 
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: E4_DYSPOLYGL – Polyglandular dysfunction
GWS hits: 1
                
                Loading Relationships table