Polyglandular dysfunction

E4_DYSPOLYGL

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E31
  • Cause of death: ICD-10 E31

2 out of 7 registries used, show all original rules.

63

4. Check minimum number of events

None

63

5. Include endpoints

71

6. Filter based on genotype QC (FinnGen only)

71

Control definitions (FinnGen only)

Control exclude E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E20-E35
Name in latin Dysfunctio polyglandularis (endocrina)

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 523 320 196
Only index persons 419 270 149
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 38.73 38.37 38.89
Only index persons 35.72 35.52 36.08

-FinnGen-

Key figures

All Female Male
Number of individuals 71 46 25
Unadjusted period prevalence (%) 0.02 0.02 0.01
Median age at first event (years) 33.02 36.10 27.34

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: E4_DYSPOLYGL – Polyglandular dysfunction

GWS hits: 1

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