No definition available.
Hypothalamic dysfunction, including iatrogenic, not elsewhere classified
E4_HYPOTHALDYSF
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditionsNone |
429209 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
61 |
4. Check minimum number of eventsNone |
61 |
5. Include endpointsNone |
61 |
6. Filter based on genotype QC (FinnGen only) |
58 |
Control definitions (FinnGen only)
Control exclude
E4_ENDOGLAND
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Hypothalamic dysfunction, including iatrogenic, not elsewhere classified
based on the number of shared cases.
Broader endpoints:
- Exclusions for E4_PCOS_BROAD
- Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT
- Disorders of other endocrine glands
- Exclusions for E4_PCOS_CONSORTIUM
- Used for control exclusion in common control thyroid runs
Narrower endpoints:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 500 | 262 | 235 |
| Only index persons | 443 | 232 | 211 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 36.55 | 37.24 | 35.34 |
| Only index persons | 34.34 | 35.41 | 33.16 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 58 | 35 | 23 |
| Unadjusted period prevalence (%) | 0.01 | 0.02 | 0.01 |
| Median age at first event (years) | 38.07 | 37.98 | 38.21 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: E4_HYPOTHALDYSF – Hypothalamic dysfunction, including iatrogenic, not elsewhere classified
GWS hits: -
Loading Relationships table