Ovarian dysfunction

E4_OVARDYS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

only females

239906

2. Check conditions

None

239906

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E28
  • Cause of death: ICD-10 E28

2 out of 7 registries used, show all original rules.

1985

4. Check minimum number of events

None

1985

5. Include endpoints

2451

6. Filter based on genotype QC (FinnGen only)

2309

Control definitions (FinnGen only)

Control exclude E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E20-E35
Name in latin Dysfunctio ovarialis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 17415 17415 -
Only index persons 16983 16983 -
Unadjusted period prevalence (%)
Whole population 0.50 0.50 -
Only index persons 0.62 0.62 -
Median age at first event (years)
Whole population - 28.41 -
Only index persons - 28.30 -

-FinnGen-

Key figures

All Female Male
Number of individuals 2309 2309 -
Unadjusted period prevalence (%) 1.00 1.00 -
Median age at first event (years) 29.81 29.81 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: E4_OVARDYS – Ovarian dysfunction

GWS hits: 6

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