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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Ovarian dysfunction: estrogen excess

E4_ODESTRO

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

only females

239906

2. Check conditions

None

239906

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E28.0#
  • Hospital discharge: ICD-9 2560
  • Hospital discharge: ICD-8 2560
  • Cause of death: ICD-10 E28.0#
  • Cause of death: ICD-9 2560
  • Cause of death: ICD-8 2560

2 out of 7 registries used, show all original rules.

41

4. Check minimum number of events

None

41

5. Include endpoints

None

41

6. Filter based on genotype QC (FinnGen only)

39

Control definitions (FinnGen only)

Control exclude E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E28
Name in latin Hypersecretio oestrogenorum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 403 403 -
Only index persons 320 320 -
Unadjusted period prevalence (%)
Whole population 0.01 0.01 -
Only index persons 0.01 0.01 -
Median age at first event (years)
Whole population - 35.28 -
Only index persons - 31.34 -

-FinnGen-

Key figures

All Female Male
Number of individuals 39 39 -
Unadjusted period prevalence (%) 0.02 0.02 -
Median age at first event (years) 29.43 29.43 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: E4_ODESTRO – Ovarian dysfunction: estrogen excess

GWS hits: -

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