Polycystic ovarian syndrome

E4_PCOS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

only females

239906

2. Check conditions

None

239906

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E28.2
  • Hospital discharge: ICD-9 2564
  • Hospital discharge: ICD-8 25690
  • Cause of death: ICD-10 E28.2
  • Cause of death: ICD-9 2564
  • Cause of death: ICD-8 25690

2 out of 7 registries used, show all original rules.

1741

4. Check minimum number of events

None

1741

5. Include endpoints

None

1741

6. Filter based on genotype QC (FinnGen only)

1639

Control definitions (FinnGen only)

Control exclude E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF6
Parent code in ICD-10 E28
Name in latin Morbus polycysticus ovariorum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 13242 13242 -
Only index persons 13074 13074 -
Unadjusted period prevalence (%)
Whole population 0.38 0.38 -
Only index persons 0.48 0.48 -
Median age at first event (years)
Whole population - 27.37 -
Only index persons - 27.35 -

-FinnGen-

Key figures

All Female Male
Number of individuals 1639 1639 -
Unadjusted period prevalence (%) 0.71 0.71 -
Median age at first event (years) 28.26 28.26 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: E4_PCOS – Polycystic ovarian syndrome

GWS hits: 5

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