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Finngen Rheumatological endpoints

RHEUMA_ENDPOINTS

rheumatic disease: Inflammatory and degenerative diseases of connective tissue structures, such as arthritis.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

104110

6. Filter based on genotype QC (FinnGen only)

100969

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 100969 58121 42848
Unadjusted period prevalence (%) 24.53 25.24 23.57
Median age at first event (years) 57.36 55.98 59.24

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: RHEUMA_ENDPOINTS – Finngen Rheumatological endpoints

GWS hits: -

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