SLE (Finngen)

SLE_FG

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

1121

6. Filter based on genotype QC (FinnGen only)

1083

Control definitions (FinnGen only)

Control exclude AUTOIMMUNE

Extra metadata

First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 8433 6670 1687
Only index persons 6978 5653 1325
Unadjusted period prevalence (%)
Whole population 0.16 0.19 0.05
Only index persons 0.18 0.21 0.05
Median age at first event (years)
Whole population 50.68 49.61 54.71
Only index persons 48.57 47.43 53.43

-FinnGen-

Key figures

All Female Male
Number of individuals 1083 898 185
Unadjusted period prevalence (%) 0.34 0.39 0.10
Median age at first event (years) 46.66 45.40 52.78

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: SLE_FG – SLE (Finngen)

GWS hits: 7

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