Osteoporosis with pathological fracture (FG)

OSTEOPOROSIS_FRACTURE_FG

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

1881

6. Filter based on genotype QC (FinnGen only)

1822

Control definitions (FinnGen only)

Control exclude RHEUMA_ENDPOINTS

Extra metadata

First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 21534 20719 796
Only index persons 19400 18718 682
Unadjusted period prevalence (%)
Whole population 0.57 0.59 0.02
Only index persons 0.66 0.69 0.03
Median age at first event (years)
Whole population 78.72 79.16 67.62
Only index persons 78.62 79.02 67.63

-FinnGen-

Key figures

All Female Male
Number of individuals 1822 1709 113
Unadjusted period prevalence (%) 0.70 0.74 0.06
Median age at first event (years) 72.22 72.48 68.31

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: OSTEOPOROSIS_FRACTURE_FG – Osteoporosis with pathological fracture (FG)

GWS hits: 2

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