Postmenopausal osteoporosis with pathological fracture

OSTPOPATFRCTURE_POSTEMENO

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

only females

239906

2. Check conditions

None

239906

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M80.0
  • Cause of death: ICD-10 M80.0

2 out of 7 registries used, show all original rules.

1539

4. Check minimum number of events

None

1539

5. Include endpoints

None

1539

6. Filter based on genotype QC (FinnGen only)

1486

Control definitions (FinnGen only)

Control exclude OSTEOPOROSIS_FRACTURE_FG

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 M80
Name in latin Osteoporosis postmenopausalis cum fractura pathologica

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 19351 19351 -
Only index persons 17522 17522 -
Unadjusted period prevalence (%)
Whole population 0.55 0.55 -
Only index persons 0.64 0.64 -
Median age at first event (years)
Whole population - 79.64 -
Only index persons - 79.50 -

-FinnGen-

Key figures

All Female Male
Number of individuals 1486 1486 -
Unadjusted period prevalence (%) 0.65 0.65 -
Median age at first event (years) 73.31 73.31 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: OSTPOPATFRCTURE_POSTEMENO – Postmenopausal osteoporosis with pathological fracture

GWS hits: 2

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