secondary hypertrophic osteoarthropathy: Symmetrical osteitis of the four limbs, chiefly localized to the phalanges and the terminal epiphyses of the long bones of the forearm and leg, sometimes extending to the proximal ends of the limbs and the flat bones, and accompanied by dorsal kyphosis and joint involvement. It is often secondary to chronic conditions of the lungs and heart. (Dorland, 27th ed)
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditionsNone |
429209 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
19480 |
4. Check minimum number of eventsNone |
19480 |
5. Include endpoints |
21887 |
6. Filter based on genotype QC (FinnGen only) |
21144 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Osteopathies and chondropathies
based on the number of shared cases.
Broader endpoints:
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
Narrower endpoints:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 238920 | 147048 | 90558 |
| Only index persons | 211296 | 130432 | 80864 |
| Unadjusted period prevalence (%) | |||
| Whole population | 3.56 | 4.21 | 2.53 |
| Only index persons | 4.14 | 4.79 | 3.09 |
| Median age at first event (years) | |||
| Whole population | 58.16 | 67.68 | 42.65 |
| Only index persons | 55.99 | 65.83 | 40.12 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 21144 | 13330 | 7814 |
| Unadjusted period prevalence (%) | 5.24 | 5.79 | 4.30 |
| Median age at first event (years) | 56.67 | 58.66 | 53.28 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: M13_OSTEOCHONDRO – Osteopathies and chondropathies
GWS hits: -
Loading Relationships table