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Osteonecrosis

DOID EFO Endpoint Browser PheWeb

M13_OSTEONECROSIS

osteonecrosis: A none disease characterized by death of bone tissue due to a lack of blood supply.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — M87
  • Hospital discharge: ICD-9 — 7334
  • Cause of death: ICD-10 — M87
  • Cause of death: ICD-9 — 7334

2 out of 7 registries used, show all original rules.

1607

4. Check minimum number of events

None

1607

5. Include endpoints

None

1607

6. Filter based on genotype QC (FinnGen only)

1543

Control definitions (FinnGen only)

Control exclude M13_OSTEOCHONDRO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M86-M90
Name in latin Osteonecrosis

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 11327 6119 5165
Only index persons 10640 5800 4840
Unadjusted period prevalence (%)
Whole population 0.16 0.18 0.14
Only index persons 0.20 0.21 0.18
Median age at first event (years)
Whole population 61.28 64.60 57.35
Only index persons 61.13 64.33 57.29

-FinnGen-

Key figures

All Female Male
Number of individuals 1543 862 681
Unadjusted period prevalence (%) 0.37 0.37 0.37
Median age at first event (years) 61.00 61.19 60.76

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: M13_OSTEONECROSIS – Osteonecrosis

GWS hits: -

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