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Disorders of continuity of bone

EFO MESH Endpoint Browser PheWeb

M13_BONECONTINUITY

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — M84
  • Cause of death: ICD-10 — M84

2 out of 7 registries used, show all original rules.

2908

4. Check minimum number of events

None

2908

5. Include endpoints

None

2908

6. Filter based on genotype QC (FinnGen only)

2821

Control definitions (FinnGen only)

Control exclude M13_OSTEOCHONDRO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M80-M85
Name in latin Perturbationes continuitatis ossis

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 29414 15578 13687
Only index persons 27495 14661 12834
Unadjusted period prevalence (%)
Whole population 0.42 0.45 0.38
Only index persons 0.52 0.54 0.49
Median age at first event (years)
Whole population 48.36 55.08 40.68
Only index persons 47.21 54.33 39.07

-FinnGen-

Key figures

All Female Male
Number of individuals 2821 1789 1032
Unadjusted period prevalence (%) 0.70 0.78 0.57
Median age at first event (years) 53.60 54.51 52.03

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: M13_BONECONTINUITY – Disorders of continuity of bone

GWS hits: 1

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