No definition available.
Drug-induced osteoporosis with pathological fracture
EFO MESH Endpoint Browser PheWeb
OSTPOPATFRACTURE
Endpoint definition
↥
						Endpoint definition steps | 
					
						FinnGen | 
				
|---|---|
						Phenotype data | 
					429209 | 
								1. Apply sex-specific ruleNone  | 
							429209 | 
								2. Check conditionsNone  | 
							429209 | 
								3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules.  | 
							
								 395  | 
						
								4. Check minimum number of eventsNone  | 
							395 | 
								5. Include endpointsNone  | 
							395 | 
										6. Filter based on genotype QC (FinnGen only) | 
									388 | 
Control definitions (FinnGen only)
					Control exclude
					OSTEOPOROSIS_FRACTURE_FG
				
			Extra metadata
					First used in FinnGen datafreeze
					DF2
				
				
					Parent code in ICD-10
					M80
				
				
					Name in latin
					Osteoporosis e medicamento cum fractura pathologica
				
			Similar endpoints
↥List of similar endpoints to
		
Drug-induced osteoporosis with pathological fracture
	based on the number of shared cases.
		
		Broader endpoints:
	
- Osteoporosis with pathological fracture (FG)
 - Osteoporosis
 - Osteopathies and chondropathies
 - Finngen Rheumatological endpoints
 - Diseases of the musculoskeletal system and connective tissue
 
		
		Narrower endpoints:
	
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2573 | 1758 | 796 | 
| Only index persons | 2250 | 1568 | 682 | 
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.05 | 0.02 | 
| Only index persons | 0.05 | 0.06 | 0.03 | 
| Median age at first event (years) | |||
| Whole population | 70.33 | 71.59 | 67.62 | 
| Only index persons | 70.23 | 71.36 | 67.63 | 
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 388 | 275 | 113 | 
| Unadjusted period prevalence (%) | 0.10 | 0.12 | 0.06 | 
| Median age at first event (years) | 67.91 | 67.74 | 68.31 | 
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: OSTPOPATFRACTURE – Drug-induced osteoporosis with pathological fracture
GWS hits: -
                
                Loading Relationships table