Reactive arthropathies, FINNGEN

RHEUMA_ARHTROPAT_REACTIVE

reactive arthritis: Reactive arthritis (ReA) is an autoimmune disorder belonging to the group of seronegative spondyloarthropathies and is characterized by the classic triad of arthritis, urethritis and conjunctivitis.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

2426

6. Filter based on genotype QC (FinnGen only)

2351

Control definitions (FinnGen only)

Control exclude RHEUMA_ENDPOINTS

Extra metadata

First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 21080 10192 10784
Only index persons 19480 9565 9915
Unadjusted period prevalence (%)
Whole population 0.30 0.29 0.30
Only index persons 0.37 0.35 0.38
Median age at first event (years)
Whole population 44.48 45.08 43.82
Only index persons 43.96 44.60 43.34

-FinnGen-

Key figures

All Female Male
Number of individuals 2351 1333 1018
Unadjusted period prevalence (%) 0.57 0.58 0.56
Median age at first event (years) 46.69 44.47 49.61

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: RHEUMA_ARHTROPAT_REACTIVE – Reactive arthropathies, FINNGEN

GWS hits: 1

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