reactive arthritis: Reactive arthritis (ReA) is an autoimmune disorder belonging to the group of seronegative spondyloarthropathies and is characterized by the classic triad of arthritis, urethritis and conjunctivitis.
Endpoint definition
↥
						Endpoint definition steps | 
					
						FinnGen | 
				
|---|---|
						Phenotype data | 
					429209 | 
								1. Apply sex-specific ruleNone  | 
							429209 | 
								2. Check conditionsNone  | 
							429209 | 
								3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules.  | 
							
								 282  | 
						
								4. Check minimum number of eventsNone  | 
							282 | 
								5. Include endpointsNone  | 
							282 | 
										6. Filter based on genotype QC (FinnGen only) | 
									277 | 
Control definitions (FinnGen only)
					Control exclude
					RHEUMA_ARHTROPAT_REACTIVE
				
			Extra metadata
					First used in FinnGen datafreeze
					DF2
				
				
					Parent code in ICD-10
					M02
				
				
					Name in latin
					Arthropathia post infectionem intestinalem
				
			Similar endpoints
↥List of similar endpoints to
		
Postdysenteric arthropathy
	based on the number of shared cases.
		
		Broader endpoints:
	
- Reactive arthropathies, FINNGEN
 - Reactive arthropathies
 - Finngen Rheumatological endpoints
 - Arthropathies
 - Diseases of the musculoskeletal system and connective tissue
 
		
		Narrower endpoints:
	
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2221 | 1079 | 1138 | 
| Only index persons | 2145 | 1048 | 1097 | 
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.03 | 0.03 | 
| Only index persons | 0.04 | 0.04 | 0.04 | 
| Median age at first event (years) | |||
| Whole population | 45.19 | 45.69 | 44.72 | 
| Only index persons | 44.97 | 45.57 | 44.40 | 
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 277 | 151 | 126 | 
| Unadjusted period prevalence (%) | 0.07 | 0.07 | 0.07 | 
| Median age at first event (years) | 46.59 | 45.78 | 47.56 | 
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: ARTRHO_POSTDYSENTERIC – Postdysenteric arthropathy
GWS hits: -
                
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