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Reactive arthropathies

DOID EFO Endpoint Browser PheWeb

M13_REACTARTH

reactive arthritis: Reactive arthritis (ReA) is an autoimmune disorder belonging to the group of seronegative spondyloarthropathies and is characterized by the classic triad of arthritis, urethritis and conjunctivitis.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — M02, M03*
  • Hospital discharge: ICD-9 — 7111|7115|7118|713
  • Hospital discharge: ICD-8 — 71490
  • Cause of death: ICD-10 — M02, M03*
  • Cause of death: ICD-9 — 7111|7115|7118|713
  • Cause of death: ICD-8 — 71490

2 out of 7 registries used, show all original rules.

3145

4. Check minimum number of events

None

3145

5. Include endpoints

None

3145

6. Filter based on genotype QC (FinnGen only)

3058

Control definitions (FinnGen only)

Control exclude M13_ARTHROPATHIES

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 28731 13789 14752
Only index persons 25824 12637 13187
Unadjusted period prevalence (%)
Whole population 0.40 0.39 0.41
Only index persons 0.48 0.46 0.50
Median age at first event (years)
Whole population 41.97 43.22 40.67
Only index persons 40.95 42.21 39.74

-FinnGen-

Key figures

All Female Male
Number of individuals 3058 1687 1371
Unadjusted period prevalence (%) 0.74 0.73 0.75
Median age at first event (years) 43.81 42.14 45.87

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: M13_REACTARTH – Reactive arthropathies

GWS hits: 1

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