Degeneration of macula and posterior pole

H7_MACULADEGEN

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

17084

4. Check minimum number of events

None

17084

5. Include endpoints

17084

6. Filter based on genotype QC (FinnGen only)

16525

Control definitions (FinnGen only)

Control exclude H7_CHOROIDRETINA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Similar endpoints

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 162685 98760 63302
Only index persons 149678 91557 58121
Unadjusted period prevalence (%)
Whole population 2.41 2.83 1.77
Only index persons 2.92 3.37 2.22
Median age at first event (years)
Whole population 75.82 76.75 74.34
Only index persons 75.40 76.34 73.92

-FinnGen-

Key figures

All Female Male
Number of individuals 16525 8604 7921
Unadjusted period prevalence (%) 4.03 3.74 4.36
Median age at first event (years) 72.73 72.01 73.52

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: H7_MACULADEGEN – Degeneration of macula and posterior pole

GWS hits: 11

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