age-related macular degeneration: Age-related loss of vision in the central portion of the retina (macula), secondary to retinal degeneration.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditionsNone |
429209 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
574 |
4. Check minimum number of eventsNone |
574 |
5. Include endpointsNone |
574 |
6. Filter based on genotype QC (FinnGen only) |
550 |
Control definitions (FinnGen only)
Control exclude
H7_CHOROIDRETINA
Extra metadata
Level in the ICD hierarchy
5
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
H35
Similar endpoints
↥List of similar endpoints to
Macular cyst
based on the number of shared cases.
Broader endpoints:
- Degeneration of macula and posterior pole
- Other retinal disorders
- Disorders of choroid and retina
- Diseases of the eye and adnexa
- Any operation in hilmo
Narrower endpoints:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3939 | 2208 | 1725 |
| Only index persons | 3877 | 2177 | 1700 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.06 | 0.05 |
| Only index persons | 0.07 | 0.08 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 72.17 | 72.28 | 72.05 |
| Only index persons | 72.18 | 72.31 | 72.02 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 550 | 303 | 247 |
| Unadjusted period prevalence (%) | 0.13 | 0.13 | 0.14 |
| Median age at first event (years) | 71.97 | 71.22 | 72.90 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: MACULAR_CYST – Macular cyst
GWS hits: 1
Loading Relationships table