age-related macular degeneration: Age-related loss of vision in the central portion of the retina (macula), secondary to retinal degeneration.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditionsNone |
429209 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
10058 |
6. Filter based on genotype QC (FinnGen only) |
9721 |
Control definitions (FinnGen only)
Extra metadata
Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF3
Similar endpoints
↥List of similar endpoints to
Age-related macular degeneration (whether dry or wet)
based on the number of shared cases.
Broader endpoints:
- Degeneration of macula and posterior pole
- Other retinal disorders
- Disorders of choroid and retina
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Narrower endpoints:
Case counts by codes
↥FinnGen case counts by registry codes:
No data for upset plot.
No data for upset table.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 108178 | 68711 | 38987 |
| Only index persons | 97698 | 62764 | 34934 |
| Unadjusted period prevalence (%) | |||
| Whole population | 1.64 | 1.97 | 1.09 |
| Only index persons | 1.96 | 2.31 | 1.33 |
| Median age at first event (years) | |||
| Whole population | 79.03 | 79.89 | 77.52 |
| Only index persons | 78.80 | 79.71 | 77.17 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 9721 | 5029 | 4692 |
| Unadjusted period prevalence (%) | 2.38 | 2.18 | 2.58 |
| Median age at first event (years) | 75.96 | 76.11 | 75.80 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: H7_AMD – Age-related macular degeneration (whether dry or wet)
GWS hits: 25
Loading Relationships table