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Primary angle-closure glaucoma

DOID EFO Endpoint Browser PheWeb

H7_GLAUCCLOSEPRIM

primary angle closure glaucoma: The sudden increase of intraocular pressure, resulting in pain and an abrupt decrease in visual acuity.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H40.2
  • Hospital discharge: ICD-9 — 3652
  • Hospital discharge: ICD-8 — 37500|37511
  • Cause of death: ICD-10 — H40.2
  • Cause of death: ICD-9 — 3652
  • Cause of death: ICD-8 — 37500|37511

2 out of 7 registries used, show all original rules.

1365

4. Check minimum number of events

None

1365

5. Include endpoints

None

1365

6. Filter based on genotype QC (FinnGen only)

1307

Control definitions (FinnGen only)

Control exclude H7_GLAUCOMA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H40
Name in latin Glaucoma congestivum primarium

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 17902 11851 5834
Only index persons 13200 8791 4409
Unadjusted period prevalence (%)
Whole population 0.28 0.34 0.16
Only index persons 0.27 0.32 0.17
Median age at first event (years)
Whole population 68.78 69.73 66.90
Only index persons 67.76 68.71 65.87

-FinnGen-

Key figures

All Female Male
Number of individuals 1307 761 546
Unadjusted period prevalence (%) 0.32 0.33 0.30
Median age at first event (years) 65.89 65.53 66.38

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: H7_GLAUCCLOSEPRIM – Primary angle-closure glaucoma

GWS hits: -

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