age-related macular degeneration: Age-related loss of vision in the central portion of the retina (macula), secondary to retinal degeneration.
Dry age-related macular degeneration (includes geographic atrophy)
DOID EFO Endpoint Browser PheWeb
DRY_AMD
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditions
|
429081 |
3. Check pre-conditions, main-only, mode, registry filtersPre-conditions: EVENT_AGE>=50 Registry filters:
2 out of 7 registries used, show all original rules. |
6884 |
4. Check minimum number of eventsNone |
6884 |
5. Include endpointsNone |
6884 |
6. Filter based on genotype QC (FinnGen only) |
6651 |
Control definitions (FinnGen only)
Control exclude
H7_RETINOPATHYDIAB, H7_RETINASEPAR, MACULA_NAS, H7_GLAUCPRIMOPEN, H7_GLAUCCLOSEPRIM, H7_GLAUCSECTRAUMA, H7_GLAUCSECINFLAM, H7_GLAUCSECDISEASE, H7_GLAUCSECDRUG, H7_GLAUCNAS
Control pre-conditions
DEATH_AGE>=50
Control conditions
not DRY_AMD_EARLY
Extra metadata
Level in the ICD hierarchy
5
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H35
Name in latin
Degeneratio maculae senilis atrophica
Similar endpoints
↥List of similar endpoints to
Dry age-related macular degeneration (includes geographic atrophy)
based on the number of shared cases.
Broader endpoints:
- Age-related macular degeneration (whether dry or wet)
- Degeneration of macula and posterior pole
- Other retinal disorders
- Disorders of choroid and retina
- Diseases of the eye and adnexa
Narrower endpoints:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 76411 | 48970 | 27076 |
| Only index persons | 68221 | 44279 | 23942 |
| Unadjusted period prevalence (%) | |||
| Whole population | 1.17 | 1.40 | 0.76 |
| Only index persons | 1.38 | 1.63 | 0.91 |
| Median age at first event (years) | |||
| Whole population | 79.61 | 80.34 | 78.29 |
| Only index persons | 79.38 | 80.14 | 77.98 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 6651 | 3513 | 3138 |
| Unadjusted period prevalence (%) | 1.62 | 1.53 | 1.73 |
| Median age at first event (years) | 76.36 | 76.39 | 76.32 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: DRY_AMD – Dry age-related macular degeneration (includes geographic atrophy)
GWS hits: 22
Loading Relationships table