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Alzheimer disease (more control exclusions)

G6_ALZHEIMER_EXMORE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G30
  • Hospital discharge: ICD-9 3310
  • Cause of death: ICD-10 G30
  • Cause of death: ICD-9 3310

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G30-G32
Name in latin Morbus Alzheimer

Case counts by codes

FinnGen case counts by registry codes:

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Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population - - -
Only index persons - - -
Unadjusted period prevalence (%)
Whole population - - -
Only index persons - - -
Median age at first event (years)
Whole population - - -
Only index persons - - -

-FinnGen-

Key figures

All Female Male
Number of individuals 10520 4620 5900
Unadjusted period prevalence (%) 2.70 2.01 3.25
Median age at first event (years) 80.14 80.00 80.25

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: G6_ALZHEIMER_EXMORE – Alzheimer disease (more control exclusions)

GWS hits: -

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