No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleNone |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpointsNone |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
Control exclude
G6_AD_WIDE, F5_DEMENTIA, F5_DEMENTIA_U, F5_PSYCH, NEURODIS, MEMLOSS, TRAUMBRAIN_NONCONCUS
Extra metadata
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Alzheimer’s disease (undefined) (more control exclusions)
based on the number of shared cases.
Broader endpoints:
- Alzheimer’s disease (undefined)
- Dementia in Alzheimer disease
- Alzheimer disease
- Alzheimer disease (more control exclusions)
- Other degenerative diseases of the nervous system
Narrower endpoints:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 12062 | 7792 | 4086 |
| Only index persons | 8572 | 5763 | 2809 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.19 | 0.22 | 0.11 |
| Only index persons | 0.18 | 0.21 | 0.11 |
| Median age at first event (years) | |||
| Whole population | 82.15 | 82.98 | 80.69 |
| Only index persons | 82.66 | 83.38 | 81.18 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 437 | 176 | 261 |
| Unadjusted period prevalence (%) | 0.12 | 0.08 | 0.14 |
| Median age at first event (years) | 80.06 | 81.59 | 79.02 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: AD_U_EXMORE – Alzheimer’s disease (undefined) (more control exclusions)
GWS hits: 3
Loading Relationships table