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severe traumatic brain injury, does not include concussion

EFO MESH Endpoint Browser PheWeb

TRAUMBRAIN_NONCONCUS

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

7662

4. Check minimum number of events

None

7662

5. Include endpoints

None

7662

6. Filter based on genotype QC (FinnGen only)

7429

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF2

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 106054 35930 68952
Only index persons 82363 29663 52700
Unadjusted period prevalence (%)
Whole population 1.61 1.03 1.93
Only index persons 1.68 1.09 2.01
Median age at first event (years)
Whole population 62.24 70.94 57.70
Only index persons 62.10 70.37 57.44

-FinnGen-

Key figures

All Female Male
Number of individuals 7429 2485 4944
Unadjusted period prevalence (%) 2.17 1.08 2.72
Median age at first event (years) 64.39 62.43 65.38

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: TRAUMBRAIN_NONCONCUS – severe traumatic brain injury, does not include concussion

GWS hits: 1

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