Other degenerative diseases of the nervous system

NEURODEGOTH

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

15093

4. Check minimum number of events

None

15093

5. Include endpoints

15255

6. Filter based on genotype QC (FinnGen only)

14703

Control definitions (FinnGen only)

Control exclude NEURODIS

Extra metadata

First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 276325 168911 105057
Only index persons 228452 143276 85176
Unadjusted period prevalence (%)
Whole population 4.09 4.84 2.94
Only index persons 4.52 5.27 3.25
Median age at first event (years)
Whole population 80.45 81.70 78.52
Only index persons 80.95 82.09 79.04

-FinnGen-

Key figures

All Female Male
Number of individuals 14703 7098 7605
Unadjusted period prevalence (%) 3.65 3.08 4.18
Median age at first event (years) 76.46 74.77 78.03

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: NEURODEGOTH – Other degenerative diseases of the nervous system

GWS hits: 6

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