Degeneration of the brain due to alcohol

G6_ALCODEGEN

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G31.2
  • Cause of death: ICD-10 G31.2

2 out of 7 registries used, show all original rules.

666

4. Check minimum number of events

None

666

5. Include endpoints

None

666

6. Filter based on genotype QC (FinnGen only)

643

Control definitions (FinnGen only)

Control exclude G6_NEURODEG

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G31
Name in latin Degeneratio systematis nervosi ex alcohol (aethylico)

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 12921 2765 9998
Only index persons 10336 2353 7983
Unadjusted period prevalence (%)
Whole population 0.24 0.08 0.28
Only index persons 0.26 0.09 0.30
Median age at first event (years)
Whole population 58.75 58.87 58.62
Only index persons 58.94 59.19 58.87

-FinnGen-

Key figures

All Female Male
Number of individuals 643 102 541
Unadjusted period prevalence (%) 0.26 0.04 0.30
Median age at first event (years) 59.67 56.52 60.26

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: G6_ALCODEGEN – Degeneration of the brain due to alcohol

GWS hits: 1

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