Circumscribed brain atrophy

G6_ATROPHCIRCUM

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G31.0
  • Hospital discharge: ICD-9 3311
  • Hospital discharge: ICD-8 34791
  • Cause of death: ICD-10 G31.0
  • Cause of death: ICD-9 3311
  • Cause of death: ICD-8 34791

2 out of 7 registries used, show all original rules.

540

4. Check minimum number of events

None

540

5. Include endpoints

None

540

6. Filter based on genotype QC (FinnGen only)

516

Control definitions (FinnGen only)

Control exclude G6_NEURODEG

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF6
Parent code in ICD-10 G31
Name in latin Atrophia cerebri circumscripta

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9185 4538 4462
Only index persons 6588 3580 3008
Unadjusted period prevalence (%)
Whole population 0.13 0.13 0.12
Only index persons 0.12 0.13 0.11
Median age at first event (years)
Whole population 66.45 69.56 63.74
Only index persons 69.18 70.86 67.17

-FinnGen-

Key figures

All Female Male
Number of individuals 516 225 291
Unadjusted period prevalence (%) 0.13 0.10 0.16
Median age at first event (years) 66.71 66.43 66.93

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: G6_ATROPHCIRCUM – Circumscribed brain atrophy

GWS hits: 1

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