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Alzheimer’s disease, wide definition (more control exclusions)

Endpoint Browser

G6_AD_WIDE_EXMORE

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

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2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — F00*, G30
  • Hospital discharge: ICD-9 — 3310
  • Hospital discharge: ICD-8 — 29010
  • Cause of death: ICD-10 — F00*, G30
  • Cause of death: ICD-9 — 3310
  • Cause of death: ICD-8 — 29010
  • KELA reimbursements: KELA codes — 307
  • KELA reimbursements: ICD-10 — F00*, G30
  • Medicine purchases: ATC — N06D

4 out of 7 registries used, show all original rules.

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4. Check minimum number of events

Min. number of events 3
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5. Include endpoints

-

6. Filter based on genotype QC (FinnGen only)

None

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Control definitions (FinnGen only)

Extra metadata

First used in FinnGen datafreeze DF3

Case counts by codes

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FinnGen case counts by registry codes:

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No upset table: script not run.

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population - - -
Only index persons - - -
Unadjusted period prevalence (%)
Whole population - - -
Only index persons - - -
Median age at first event (years)
Whole population - - -
Only index persons - - -

-FinnGen-

Key figures

All Female Male
Number of individuals 15617 6875 8742
Unadjusted period prevalence (%) 4.01 2.99 4.81
Median age at first event (years) 79.07 79.16 79.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: G6_AD_WIDE_EXMORE – Alzheimer’s disease, wide definition (more control exclusions)

GWS hits: -

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