No definition available.
Endpoint definition
↥
						Endpoint definition steps | 
					
						FinnGen | 
				
|---|---|
						Phenotype data | 
					429209 | 
								1. Apply sex-specific ruleNone  | 
							429209 | 
								2. Check conditionsNone  | 
							429209 | 
								3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules.  | 
							
								 0  | 
						
								4. Check minimum number of eventsNone  | 
							0 | 
								5. Include endpoints | 
							7592 | 
										6. Filter based on genotype QC (FinnGen only) | 
									7231 | 
Control definitions (FinnGen only)
					Control exclude
					F5_SUBSTANCE
				
			Extra metadata
					Level in the ICD hierarchy
					C
				
				
					First used in FinnGen datafreeze
					DF2
				
			Similar endpoints
↥List of similar endpoints to
		
Substance use, excluding alcohol
	based on the number of shared cases.
		
		Broader endpoints:
	
- Substance abuse
 - Substance abuse (more control exclusions)
 - Mental and behavioural disorders due to psychoactive substance use
 - Any mental disorder
 - Psychiatric diseases
 
		
		Narrower endpoints:
	
- Mental and behavioural disorders due to multiple drug use and use of multiple drugs and use of other psychoactive substances
 - Mental and behavioural disorders due to tobacco
 - Smoking dependency
 - Mental and behavioural disorders due to sedatives or hypnotics
 - Mental and behavioural disorders due to opioids
 
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 98359 | 36314 | 61289 | 
| Only index persons | 83970 | 32300 | 51670 | 
| Unadjusted period prevalence (%) | |||
| Whole population | 1.46 | 1.04 | 1.71 | 
| Only index persons | 1.67 | 1.19 | 1.97 | 
| Median age at first event (years) | |||
| Whole population | 34.02 | 37.28 | 32.00 | 
| Only index persons | 32.54 | 35.38 | 30.77 | 
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 7231 | 3400 | 3831 | 
| Unadjusted period prevalence (%) | 1.81 | 1.48 | 2.11 | 
| Median age at first event (years) | 39.56 | 40.09 | 39.09 | 
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: F5_SUBSNOALCO – Substance use, excluding alcohol
GWS hits: 3
                
                Loading Relationships table