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Mental and behavioural disorders due to use of volatile solvents

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F5_SOLVENT

alcohol withdrawal delirium: An acute organic mental disorder induced by cessation or reduction in chronic alcohol consumption. Clinical characteristics include confusion; delusions; vivid hallucinations; tremor; agitation; insomnia; and signs of autonomic hyperactivity (e.g., elevated blood pressure and heart rate, dilated pupils, and diaphoresis). This condition may occasionally be fatal. It was formerly called delirium tremens. (From Adams et al., Principles of Neurology, 6th ed, p1175)

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — F18
  • Hospital discharge: ICD-9 — 3046
  • Cause of death: ICD-10 — F18
  • Cause of death: ICD-9 — 3046

2 out of 7 registries used, show all original rules.

86

4. Check minimum number of events

None

86

5. Include endpoints

None

86

6. Filter based on genotype QC (FinnGen only)

81

Control definitions (FinnGen only)

Control exclude F5_SUBSNOALCO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F10-F19
Name in latin Perturbationes mentis et modi se gerendi ex usu solventium volatilium

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1225 317 902
Only index persons 1060 291 769
Unadjusted period prevalence (%)
Whole population 0.02 0.01 0.03
Only index persons 0.02 0.01 0.03
Median age at first event (years)
Whole population 28.99 26.78 29.71
Only index persons 28.18 26.16 28.94

-FinnGen-

Key figures

All Female Male
Number of individuals 81 29 52
Unadjusted period prevalence (%) 0.02 0.01 0.03
Median age at first event (years) 26.96 24.99 28.06

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: F5_SOLVENT – Mental and behavioural disorders due to use of volatile solvents

GWS hits: 1

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